Atypical fibroxanthoma is a type of skin cancer that typically occurs on the head and neck of older people who have had lots of sun damage. It is not usually thought of with the more common skin cancers, such as basal or squamous cell carcinomas, but it is considered to be skin cancer. Atypical fibroxanthoma usually appear as pink-red raise areas

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Mohs surgery with ≥2 cm safety margins is the treatment of choice. A regular follow‐up is recommended. © 2014 Wiley Periodicals, Inc. Head Neck 37: 829–834, 2015 Atypical fibroxanthoma (AFX) is the most common of the rare cutaneous malignancies. AFX usually involves sites of high cumulative ultraviolet exposure and is rarely located in the periocular region. We are aware of 7 case reports in the literature, of periocular AFX, one of which was treated with Mohs Micrographic Surgery (MMS). Seavolt M, McCall M (2006) Atypical fibroxanthoma: review of the literature and summary of 13 patients treated with mohs micrographic surgery. Dermatol Surg 32: 435-441.

Treatment of atypical fibroxanthoma of the skin (AFX) includes curettage and dessication (C&D), wide local excision (WLE), and Mohs micrographic surgery (MMS). Although all three are within the standard of care, the same Mayo clinic review found significant differences in recurrence rates. 2020-10-14 A comparison of Mohs micrographic surgery and wide excision for the treatment of atypical fibroxanthoma. Dermatol Surg 1997;23:105-110. PubMed 8. Jacobs DS, Edwards WD, Ye RC. Metastatic atypical fibroxanthoma of skin.

What is Atypical Fibroxanthoma? An Atypical Fibroxanthoma (AFX) is an uncommon (< 0.2 % of all skin cancers) type of skin cancer that occurs mainly in older people after the skin of the head and neck has been damaged by sunlight and/or by radiotherapy used to treat a previous cancer. What causes Atypical Fibroxanthoma?

A previous case of atypical fibroxanthoma (AFX) surrounding a trichilemmal cyst with squamous cell carcinoma in situ (SCCis) arising within its wall has been 6 Jun 2016 Keloidal atypical fibroxanthoma (KAF) has recently been categorized as Wide local excision with frozen section control or Mohs micrographic Histiocytoma and Atypical. Fibrous brosarcoma protuberans (DFSP), atypical fibroxanthoma. (AFX) tumors) and 5 patients with AFX with Mohs micrographic.

Low grade malignant cutaneous neoplasm. Usually presents on the sun exposed skin (e.g. head and neck) of elderly patients with a slight male predominance. Histologically, a dermal based, well circumscribed tumor composed of pleomorphic, irregularly arranged, spindled to epithelioid cells with numerous mitotic figures.

Malignant perifollicular atypical fibroxanthoma treated with Mohs surgery. Dudelzak J(1), Sheehan DJ, Mullins SC, Peterson CM. Author information: (1)Division of Dermatology, Department of Medicine, Augusta, Georgia 30912, USA. Atypical fibroxanthoma (AFX) is a rare, rapidly growing mesenchymal neoplasm that often presents on sun-exposed head and neck regions of older individuals. The diagnosis relies on knowledge of its clinical and histological features combined with immunohistochemistry markers used primarily to exclude other cutaneous neoplasms that may share Atypical fibroxanthoma (AFX) is the most common of the rare cutaneous malignancies.

Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy.
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In April 2014, approximately 8 months after the Mohs excision, a 1.1-cm nodule recurred at the center of the previous Mohs excision site. The lesion was excised with single-stage Mohs micrographic surgery Uderm - Dermatology & Mohs Surgery, Ooltewah, Tennessee. 311 likes · 4 talking about this · 7 were here. Accepting New Patients!! Uderm, PLLC is a locally-based dermatology practice offering Mohs Specialist | Mohs Surgeon | Houston | The Woodlands | Springs | Katy.

A systematic retrospective review of the literature focusing on treatment modality found a recur …. Atypical fibroxanthoma (AFX) is a dermal spindle-cell sarcoma that is considered a superficial and clinically benign presentation of pleomorphic dermal sarcoma, malignant fibrous histiocytoma, and undifferentiated pleomorphic sarcoma.
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Features eight all-new chapters on Atypical Fibroxanthoma, Confluent and Reticulated Mohs Surgery Appropriate Use Criteria. Medicin.

Large trials comparing Mohs to standard excision for other types of skin cancer are lacking.